Like the barberry Oregon grape contains the alkaloids berberine, berbamine, canadine, and hydrastine.
It is believed that these alkaloids inhibit the ability of bacteria, such as E. coli, to attach to human cells and thus prevent the spread of infection.
There is some evidence that as an ointment Oregon grape may alleviate the symptoms of psoriasis.
It is also used in small doses to treat diarrhea and in larger doses to treat constipation.
One of the primary actions of this herb is an improvement of blood flow to the liver. It also stimulates intestinal secretions and bile flow.
It is sometimes used in the treatment of jaundice, hepatitis, cirrhosis and general digestive problems.
Laboratory tests have shown that Oregon grape can kill or suppress the growth of candida and other fungal infections, staphylococcus, streptococcus, E. coli, Entamoeba histolytica, Trichomonas vaginalis, Giardia lamblia, Vibrio cholerae, and other harmful microbes.
Animal studies have indicated that it may enhance the performance of some antibiotics. No results from clinical trials are available at this time.
A tincture of the herb is used traditionally as both oral and topical herbal remedy to treat eczema, acne, conjunctivitis and herpes.
Additional historical and traditional uses include the treatment of gall bladder disease, hemorrhages and a few forms of cancer.
Native American tribes used Mahonia aquifolium as a treatment for fungal infections, skin problems and dysentery. These early Americans were aware of the herb’s anti-inflammatory properties.
It is most thoroughly researched in the treatment of skin irritations and disorders, but studies of the effectiveness of the herb as a treatment for fungal infections, acne and eczema are very preliminary and inconclusive.
Oregon grape shows promise as a treatment for autoimmune diseases of the skin, but there are currently no conclusive clinical results. A herbalist or physician can provide advice on whether this treatment is suitable for an individual patient.
In addition to berberine and other alkaloids, also found in barberry and goldenseal, Oregon grape contains phytochemicals, including jatrorrhizine, hydrastine, columbamine, tetrahydroberberine, tannins and oxyacanthine.
Barberry contains more nutrients and vitamins, but it is thought that both barberry and Oregon grape help boost the immune system and create a barrier to bacteria in the lining of the intestines and the mucous membranes.
[Read more about Oregon Grape…]
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